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교수진

김동휘

  • 직위 교수
  • TEL 02-3290-4615
  • Fax 02-921-0688
  • E-mail donghweekim@korea.ac.kr
  • Office 고려대학교 KU R&D 센터 4층 416A호
  • 연구실 Applied Mechanobiology Group

세부전공

  • Cellular Mechanobiology
  • Disease Biophysics
  • Physics of Cancer
  • Digital Pathology
  • Organ on a Chip

학력

  • 2008.09 ~ 2012.12Chemical and Biomolecular Engineering, Johns Hopkins University (Ph. D.)
  • 2005.02 ~ 2007.02Chemical and Biomolecular Engineering, KAIST (M. S.)
  • 1999.03 ~ 2005.02Chemical and Biological Engineering, Korea University (B. S.)

경력

  • 2020.09 ~ Head, Major in Medical Convergence Engineering
  • 2019.09 ~ Associate Professor, Korea University, S.Korea
  • 2015.09 ~ 2019.08Assistant Professor, Korea University, S.Korea
  • 2014 ~ 2015Postdoctoral Fellow, Harvard University, USA
  • 2013 ~ 2014Postdoctoral Fellow, Johns Hopkins Institute for NanoBioTechnology, USA
  • 2007 ~ 2007Research Scientist, Korea Research Institute of Chemical Technology, S.Korea
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학회경력

  • 2020 ~ Guest Editor, Micromachines, MDPI, Basel, Switzerland
  • 2020 ~ Young researcher Committee, Korean Tissue Engineering and Regenerative Medicine Society (KTERMS)
  • 2018 ~ Academic Committee, Korean Society for Biomaterials (KSBM)
  • 2018 ~ 2018Organizing Committee, IEEE Nanomed, USA
  • 2017 ~ ASCB Korean Ambassador, American Society for Cell Biology (ASCB), USA
  • 2017 ~ Intellectual Property Evaluation Committee, Institute of Basic Science (IBS)
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등록학회

  • Korean Physical Society
  • Korean BioChip Society
  • Korean Society for Biomaterials
  • Korean Tissue Engineering and Regenerative Medicine Society
  • Korean Society of Applied Pharmacology
  • Korean Society for Molecular and Cellular Biology
  • Korean Society of Industrial and Engineering Chemistry
  • Korean Society for Biotechnology and Bioengineering
  • Korean Society for Nanomedicine
  • Biomedical Engineering Society (USA)
  • Biophysical Society (USA)
  • American Society for Cell Biology (USA)
  • The Polymer Society of Korea
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수상

  • [국내]2020.11

    Phi Biomed Young Scientist Award, The Korean Society for Biomaterials (KSBM)

  • [국내]2018.02

    International Relations Committee Award, Biophysical Society (BPS)

  • [국외]2016.10

    The 1st Young Scientist Award, The Korean Society of Industrial and Engineering Chemistry (KSIEC)

  • [국외]2016.02

    International Relations Committee Award, Biophysical Society (BPS)

  • [국외]2013.12

    2nd place winner, The Art of Science, Biophysical Society (BPS)

  • [국내]2011.07

    Honorable Mention, Cell Dance, American Society for Cell Biology (ASCB)

  • [국내]2011.02

    Image of Distinction, 2011 Nikon small world competition

  • [국내]2005.02

    Summa Cum Laude, Korea University

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주요논문

2021
  • Lee G#, Han SB#, Kim DH*. Cell-ECM contact-guided intracellular polarization is mediated via Lamin A/C dependent nucleus-cytoskeletal connection, Biomaterials (2021)
  • Han SB, Won B, Yang SC, Kim DH*. Asterias pectinifera derived collagen peptide-encapsulating elastic nanoliposomes for the cosmetic application, Journal of Industrial and Engineering Chemistry (2021)
  • Min S, Ko MJ, Jung HJ, Kim W, Han SB, Kim Y, Bae G, Lee S, Thangam R, Choi H, Li N, Shin JE, Jeon YS, Park HS, Kim YJ, Sukumar UK, Song JJ, Park SK, Yu SH, Kang YC, Lee KB, Wei Q, Kim DH, Han SM, Paulmurugan R, Kim YK, Kang H. Remote control of time-regulated stretching of ligand-presenting nanocoils in situ regulates the cyclic adhesion and differentiation of stem cellsIn situ ligand stretching, Advanced Materials (2021)
2020
  • Jo J#, Abdi Nansa S#, Kim DH*. Molecular regulators of cellular mechanoadaptation at cell-material interfaces, Frontiers in Bioengineering and Biotechnology (2020)
  • Han SB#, Kim JK#, Lee G, Kim DH*. Mechanical properties of materials for stem cell differentiation, Advanced Biosystems (2020)
  • Park JW#, Han SB#, Hah J, Lee G, Kim JK, Kim SH, Kim DH*. Biological aging modulates cell migration via lamin A/C dependent nuclear motion. Micromachines (2020)
  • Ko GJ, Han SD, Kim JK, Zhu J, Han WB, Chung J, Yang SM, Cheng H, Kim DH, Kang CY, Hwang SW*. Biodegradable, flexible silicon nanomembranes-based NOx gas sensor system with record-high performance for transient environmental monitors and medical implants. NPG Asia Materials (2020)
  • Lee YJ, Lee BY, Yoon CW, Jeong H, Jang SC, Kim DH, Kim KB, Nam SW*. Facile synthesis of micro-sized Ni-Al alloy powders through low-temperature chemical alloying. Journal of Alloys and Compounds (2020)
2019
  • Lee GH, Han SB#, Lee JH, Kim HW, Kim DH*. Cancer mechanobiology: Microenvironmental sensing and metastasis, ACS Biomaterials Science & Engineering (2019)
  • Shafiq M, Wang L, Zhang Q, Kim DH, Kong D, Kim SH*. In Situ Blood Vessel Regeneration using Neuropeptide Substance P Conjugated Small-Diameter Vascular Grafts. Journal of Biomedical Materials Research: Part B - Applied Biomaterials (2019)
  • Sneider A, Hah J, Wirtz D*, Kim DH*. Recapitulation Of Nuclear Motion During Cell Migration. Cell Adhesion & Migration (2019)
  • Hah J, Kim DH*. Deciphering nuclear mechanobiology in laminopathy, Cells (2019)
  • Lee JH, Kim DH, Lee HH, Kim HW*. Role of nuclear mechanosensitivity in determining cellular responses to forces and biomaterials, Biomaterials (2019)
  • Kim JK, Shin YJ, Ha LJ, Kim DH, Kim DH*. Unraveling the mechanobiology of immune system, Advanced Healthcare Materials (2019)
2018
  • Kim DH*, Hah J, Wirtz D. Mechanics of the Cell Nucleus. Biomechanics in Oncology. Advances in Experimental Medicine and Biology (2018)
  • Shafiq M, Zhang Y, Zhu D, Zhao Z, Kim DH, Kim SH, Kong D*. In situ cardiac regeneration by using neuropeptide substance P and IGF-1C peptide eluting heart patches. Regenerative Biomaterials (2018)
  • Kih M, Lee EJ, Lee NK, Lee KE, Kim YK, Jeong C, Yang Y, Kim DH, Kim IS*. Designed trimer-mimetic TNF superfamily ligands on self-assembling nanocages. Biomaterials (2018)
  • Shafiq M, Zhang Q, Zhi D, Wang K, Kong D, Kim DH, Kim SH*. In Situ Blood Vessel Regeneration using Substance P and SDF-1α Peptide Eluting Vascular Grafts. Arteriosclerosis, Thrombosis, and Vascular Biology (2018)
  • Lee G, Lim J, Park J, Lee W, Yoon DS, Kim MK*, Lee SH, Kim DH*. Construction of micro-brains via surface modified concave microwells. Journal of Industrial and Engineering Chemistry (2018)
  • Cho E, Nam GH, Hong Y, Kim DH, Yang Y, Kim IS*. Comparison of exosomes and ferritin protein nanocages for the delivery of membrane protein therapeutics. Journal of Controlled Release (2018)
  • Lee G, Lee J, Lee GH, Joung WY, Kim SH, Lee SH, Park JY, Kim DH*. Network concave microwell arrays for constructing three dimensional cell spheroids. Biofabrication (2018)
  • Hong Y, Nam GH, Koh E, Jeon S, Kim GB, Jeong C, Kim DH, Yang Y, Kim IS*. Exosome as a vehicle for delivery of membrane protein therapeutics, PH20 for enhanced tumor penetration and anti-tumor efficacy. Advanced Functional Materials (2018)
  • Lee G, Jun Y, Jang HY, Yoon J, Lee J, Hong M, Chung S*, Kim DH*, Lee SH. Enhanced oxygen permeability improves the functionality of three dimensional pancreatic islet spheroids in the engineered concave microwells. Acta Biomaterialia (2018)
2017
  • Kim JK, Louhghalam A, Lee GH, Wirtz D, Schafer BW, Kim DH*. Nuclear lamin A/C harnesses the perinuclear actin cables to protect nuclear morphology. Nature Communications (2017)
  • Lee TH, Hwang HG, Jang S, Wang G, Han SB, Kim DH, Kang CY, Nahm S. Low temperature-grown KNbO3 thin films and their application to piezoelectric nanogenerators and self-powered ReRAM device. ACS Applied Materials & Interfaces (2017)
2016
  • Hecht VC, Sullivan LB, Kimmerling R, Kim DH, Hosios AM, Stevens MM, Kang JH, Wirtz D, Vander Heiden MG, Manalis SR. Biophysical changes reduce energetic demand in growth factor-deprived lymphocytes. Journal of Cell Biology (2016)
2015
  • Kim DH*, Wirtz D. Cytoskeletal tension induces the polarized architecture of the nucleus. Biomaterials (2015)
  • Kim DH, Li B, Si F, Philip J, Wirtz D, Sun SX. Volume regulation and shape bifurcation in the eukaryotic nucleus. Journal of Cell Science (2015)
2014
  • Kim DH*, Cho SK, Wirtz D. Tight coupling between nucleus and cell migration through the perinuclear actin cap. Journal of Cell Science (2014)
2013
  • Kim DH, Chambliss A, Wirtz D. The multi-faceted role of the actin cap in cellular mechanosensation and mechanotransduction. Soft Matter (2013)
  • Kim DH, Wirtz D. Predicting how cells spread and migrate: Focal adhesion size does matter. Cell adhesions & migration (2013)
  • Kim DH, Wirtz D. Focal adhesion size uniquely predicts cell migration. FASEB Journal (2013)
2012
  • Kim DH, Khatau SB, Feng Y, Walcott S, Sun SX, Longmore GD, Wirtz D. Actin cap associated focal adhesions and their distinct role in cellular mechanosensing. Scientific Reports (2012)
2011
  • Kim DH, Wirtz D. Recapitulating cancer cell invasion in vitro. Proceedings of the National Academy of Sciences USA (2011)
  • Walcott S, Kim DH, Wirtz D, Sun SX. Nucleation and decay initiation are the stiffness sensitive phases of focal adhesion maturation. Biophysical Journal (2011)
  • Kim HK, Kim DH, Choi J, Kim SC. Compositional effect on the properties of sulfonated and nonsulfonated polymer blend membranes for direct methanol fuel cell. Macromolecular Research (2011)
2010
  • .Fraley SI, Feng Y, Krishnamurthy R, Kim DH, Celedon A, Longmore GD, Wirtz D. A distinctive role for focal adhesion proteins in three-dimensional cell motility. Nature Cell Biology (2010)
  • Khatau SB, Kim DH, Hale CM, Bloom RJ, Wirtz D. The perinuclear actin cap in health and disease. Nucleus (2010)
2008
  • Kim DH, Kim SC. Transport properties of polymer blend membranes of sulfonated and nonsulfonatedpolysulfone for direct methanol fuel cell application. Macromolecular Research (2008)
  • Choi J, Kim DH, Kim SC. Polymer blend membranes of sulfonated poly(arylene ether ketone) for direct methanol fuel cell. Journal of Membrane Science (2008)
2007
  • Kim DH, Choi J, Hong YT, Kim SC. Phase separation and morphology control of polymer blend membranes of sulfonated and nonsulfonated polysulfone for direct methanol fuel cell. Journal of Membrane Science (2007)
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특허

2020
  • Method for Obtaining Collagen Peptide from Starfish

    [출원번호]KR-10-2020-0059674
  • Extracellular matrix micropatterns to control cell polarity

    [출원번호]KR-10-2020-0172652
2019
  • Surface modified microplatform for culturing 3-D neuronal spheroid with neurite formation.

    [출원번호]PCT/KR2019/018382
2018
  • Kim DH, Lee GH, Park JW, Han SB, Oxygen permeability controllable chip for 3D cell culture

    [등록번호]KR-10-1894279
2017
  • Kim DH, Seo HS, Kim JK. Early diagnostic platform for ischemic heart disease using high-throughput cell phenotyping method

    [출원번호]10-2017-0016383
2007
  • Kim SC, Kim DH. Polymer blend membranes for fuel cells and fuel cells comprising the same.

    [등록번호]KR-10-0853713
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