논문
Virus-Mimetic Fusogenic Exosomes for Direct Delivery of Integral Membrane Proteins to Target Cell Membranes
구분 : International Journal 저자 : Yang Y, Hong Y, Nam GH, Chung JH, Koh E, Kim IS 게재년월 : 2017.04 게재지 : ADVANCED MATERIALS
An efficient system for direct delivery of integral membrane proteins is successfully developed using a new biocompatible exosome-based platform. Fusogenic exosomes harboring viral fusogen, vascular stomatitis virus (VSV)-G protein, can fuse with and modify plasma membranes in a process called “membrane editing.” This can facilitate the transfer of biologically active membrane proteins into the target cell membranes both in vitro and in vivo.
